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Summary Overview Articles

Product Authenticity

Jasper, J. P. (2004). Pharmaceutical security: Using stable isotopes to authenticate pharmaceutical materials. Tablets and Capsules 2(3):37-42.

Process Authenticity

Process Analytical Chemistry and Process Patent Protection

Sabatelli, A.D., A. Pearson, and J.P. Jasper (2017). Process patent protection via analysis of stable isotope ratios. Org. Proc. Res. Dev. 21(7):956-965.

Jasper, J. P., L. E. Weaner, and J. M. Hayes (2007). Process Patent Protection: Characterizing synthetic pathways by stable-isotopic measurements. Pharm. Technol. 31(3):68-73.

Jasper, J. P., R.C. Lyon, and L.E. Weaner (2005). Stable isotopes provide a new PAT [Process Analytical Technology] tool. Pharm. Mfg. 4(5):28-33.

Summary Advertisement

Molecular Isotope Technologies advertisement (January, 2004). We can differentiate sources of drugs by their natural "fingerprints." Pharm. Technol.

Scientific and News Articles

Jasper, J. P., P. Farina, A. Pearson, P. S. Mezes, and A. D. Sabatelli (2016). Evaluating practical uses of molecular isotopic engineering. Pharm. Tech. 40(7):34-45.

Jasper, J. P., P. Farina, A. Pearson, P. S. Mezes, and A. D. Sabatelli (2016). Molecular Isotopic Engineering (MIE): Industrial Manufacture of Naproxen of Predetermined Stable Carbon-Isotopic Compositions for Authenticity and Security Protection and Intellectual Property Considerations. SPIE Reports. 8pp.

Jasper, J.P., Zhang, F., Poe, R.B., and Linhardt, R.J. (2015). Stable-Isotopic Analysis of Porcine, Bovine, and Ovine Heparins. J. Pharm. Sci. 104:457–463.

Anthony D. Sabatelli. Connecticut High-Tech Company Uses “Nature’s Fingerprint®” To Add Value to Patent Portfolios Pharm. Mfg.

Wokovich, A.M., J.A. Spencer, B.J. Westenberger, L.F. Buhse, and J.P. Jasper. (2005). Stable isotopic composition of the active pharmaceutical ingredient (API) Naproxen. J. Pharm. Biomed. Anal., 38:781-784.

Jasper, J. P., L. E. Weaner, and B. J. Duffy (2005). A preliminary multi-stable-isotopic evaluation of three synthetic pathways of Topiramate. J. Pharm. Biomed. Anal. 39:66-75.

Jasper, J. P., L. E. Weaner, and B. J. Duffy (2004). A preliminary multi-stable isotopic evaluation of Topiramate. Forensic Isotope Ratio Mass Spectrometry (FIRMS) Newsletter 2(2):8-9.

Jasper, J. P., B. J. Westenberger, J. A. Spencer, L. F. Buhse, and M. Nasr (2004). Stable isotopic characterization of active pharmaceutical ingredients. J. Pharm. Biomed. Anal. 35:21-30

Authentication News (2004). Two new FDA studies cover stable isotopic authentication. June 2004 10(5):5.

Jasper, J. P., F. Fourel, A. Eaton, J. Morrison, and A. Phillips (2004). Stable isotopic characterization of analgesic drugs. Pharm. Technol. 28(8):60-67, (abstract presented at May, 2001 Am. Soc. Mass Spec., Chicago, Illinois).

Jasper, J. P., J. S. Edwards, L. C. Ford and R.A. Corry. (2002). Putting the arsonist at the scene: "DNA" for the fire investigator? Gas chromatography/isotope ratio mass spectrometry. Fire Arson Investig.51(2): 30-34.

(Also see A Novel Method for Arson Analysis.)

Jasper, J. P. (2001). Quantitative estimates of precision for molecular isotopic measurements. Rap. Comm. Mass Spec. 15:1554-1557.

For any questions regarding these papers, please contact Dr. John Jasper. articles link to pdf documents - download a free adobe reader